Turning off this newly discovered brain pathway could help us block fearful memories

Scientists now know how to make you forget your fears — at least if you’re a mouse. By turning off a newly discovered brain pathway, scientists were able to make mice lose their fear of a shock. It’s early research, but it may point toward methods that could help people with anxiety and PTSD.

After finding a new pathway in the brain important for creating fearful memories, scientists trained mice to fear a high-pitched tone by shocking the rodents every time they heard it, according to a study published today in Nature Neuroscience. They waited til the rodents would freeze in fear even without the shock before proceeding to the next stage: viewing the mouse brains. Using a specialized microscopy technique, the scientists observed that there was growth in the neurons along that pathway. So what would happen if they could turn that pathway off?

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