“Throw out the textbooks” and “missing link” are words rarely heard anymore in science, but that’s what researchers around the world are saying about the recent discovery of microscopic lymphatic vessels connecting the brain to the immune system.
That physical link was long thought absent, confounding scientists who study neurological disorders with an immune component. The vessels were found in mice, by accident, by University of Virginia researchers who published their results in Nature. If confirmed in humans, experts say, the discovery could have profound implications for a range of conditions including chronic fatigue syndrome, autism, multiple sclerosis and Alzheimer’s disease.
Lymphatic vessels, which piggyback on blood vessels, distribute immune cells to tissues to fight infection and carry fluid away from tissues to dispose of cellular waste. This complex drainage system has been found in nearly every part of the human body but not, until now, in the brain.